Ribozyme

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	**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />		**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />
	**[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR />		**[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR />
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	*Various ribozymes		*Various ribozymes
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	**[[4qjh]] – twister RZ – synthetic<br />		**[[4qjh]] – twister RZ – synthetic<br />
	**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br />		**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br />
-	**[[1u6b]], [[1zzn]], [[3bo2]], [[3bo3]], [[3bo4]], [[3iin]] - ''Azoarcus'' group I intron <br/>	+	**[[5k7c]],[[5k7d]],[[5k7e]] - pistol RZ - synthetic <br/>
	}}		}}
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	== References ==		== References ==
	<references/>		<references/>
	[[Category: Topic Page]]		[[Category: Topic Page]]

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Revision as of 17:20, 22 August 2016

spinqualitylabelsall models Hammerhead ribozyme, 379d Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction^[1].

• Glucosamine-6-phosphate activated RZ (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.
  
• Leadzyme is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see Student Projects for UMass Chemistry 423 Spring 2012-10.
  
• Hairpin RZ and hammerhead RZ are named based on their shape^[2].
  
• Group I intron catalyzes its own selfish splicing^[3].

Articles in Proteopedia concerning ribozymes include:

• Azoarcus group I intron
• Kink-turn motif
• Ribosome
• The Large Ribosomal Subunit
• Hairpin Ribozyme
• Human CPEB3 ribozyme's P4 domain

To view automatically seeded indices concerning ribozymes, see:

• Ribozyme
• Catalytic RNA
• GlmS
• Hammerhead
• Hairpin
• Hepatitis delta virus
• Twister
• Twister sister
• Hatchet
• Pistol
• Group I intron
• Varkud satellite

3D Structures of Ribozymes

Updated on 22-August-2016

References

1. ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
2. ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
3. ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551