Symporter

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*Di-or tripeptide:H+ symporter
*Di-or tripeptide:H+ symporter
-
**[[4ja4]], [[4xni]], [[4d2b]], [[4aps]] – StSymp – ''Streptococcus thermophilus''<BR />
+
**[[4ja4]], [[4xni]], [[4xnj]], [[4d2b]], [[4aps]], [[5d6k]] – StSymp – ''Streptococcus thermophilus''<BR />
**[[4d2d]] – StSymp + tripeptide<BR />
**[[4d2d]] – StSymp + tripeptide<BR />
-
**[[4d2c]] – StSymp + dipeptide<BR />
+
**[[4d2c]], [[5d58]], [[5d59]] – StSymp + dipeptide<BR />
*Proton:oligopeptide symporter
*Proton:oligopeptide symporter
Line 47: Line 47:
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
**[[3dh4]] – VpSymp + galactose <BR />
**[[3dh4]] – VpSymp + galactose <BR />
 +
 +
*Sodium/citrate symporter
 +
 +
**[[5a1s]] – Symp + citrate – ''Salmonella enterica''<BR />
 +
 +
*Purine/H+ symporter
 +
 +
**[[5i6c]] – Symp + xanthine – ''Aspergillus nidulans''<BR />
 +
}}
}}
== References ==
== References ==
<references/>
<references/>

Revision as of 09:07, 6 September 2016

Dipeptide:H+ symporter (grey) complex with dipeptide (yellow), lipid and phosphate (PDB code 4d2c)

Drag the structure with the mouse to rotate

3D Structures of symporter

Updated on 06-September-2016

References

  1. Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev. 2003 Feb;24(1):48-77. PMID:12588808 doi:http://dx.doi.org/10.1210/er.2001-0029
  2. Pohlenz J, Refetoff S. Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism. Biochimie. 1999 May;81(5):469-76. PMID:10403177
  3. Lyons JA, Parker JL, Solcan N, Brinth A, Li D, Shah ST, Caffrey M, Newstead S. Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters. EMBO Rep. 2014 Jun 10. pii: e201338403. PMID:24916388 doi:http://dx.doi.org/10.15252/embr.201338403

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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