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TATA-Binding Protein

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<scene name='TATA-Binding_Protein/Symmetrical/5'>two symmetrical halves</scene>.
<scene name='TATA-Binding_Protein/Symmetrical/5'>two symmetrical halves</scene>.
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The interactions of TBP with the DNA TATA box occurs with the minor groove of the DNA. The DNA duplex is bent in a sharp angle and most interactions are non-polar of hydrophobic<ref>PMID:8757291</ref>.
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Revision as of 08:08, 7 September 2016

Yeast TATA-binding protein dimer complex with DNA TATA box (PDB code 1tgh)

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3D Structures of TATA-binding protein

Updated on 07-September-2016

References

  1. ↑ Caporaso N. Genetic susceptibility in the occupational setting: introduction to the workshop. Med Lav. 1995 May-Jun;86(3):199-206. PMID:7565278
  2. ↑ van Roon-Mom WM, Reid SJ, Faull RL, Snell RG. TATA-binding protein in neurodegenerative disease. Neuroscience. 2005;133(4):863-72. PMID:15916858 doi:http://dx.doi.org/10.1016/j.neuroscience.2005.03.024
  3. ↑ Juo ZS, Chiu TK, Leiberman PM, Baikalov I, Berk AJ, Dickerson RE. How proteins recognize the TATA box. J Mol Biol. 1996 Aug 16;261(2):239-54. PMID:8757291 doi:10.1006/jmbi.1996.0456

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