5jrz

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Revision as of 05:33, 9 September 2016

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 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jrz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jrz OCA], [http://pdbe.org/5jrz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jrz RCSB], [http://www.ebi.ac.uk/pdbsum/5jrz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jrz ProSAT]</span></td></tr>
 </table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Zika virus has emerged as a pathogen of major health concern. Here, we present a high-resolution (1.62-A) crystal structure of the RNA helicase from the French Polynesia strain. The structure is similar to that of the RNA helicase from Dengue virus, with variability in the conformations of loops typically involved in binding ATP and RNA. We identify druggable 'hotspots' that are well suited for in silico and/or fragment-based high-throughput drug discovery.
+Structure of the NS3 helicase from Zika virus.,Jain R, Coloma J, Garcia-Sastre A, Aggarwal AK Nat Struct Mol Biol. 2016 Aug;23(8):752-4. doi: 10.1038/nsmb.3258. Epub 2016 Jul , 11. PMID:27399257<ref>PMID:27399257</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 5jrz" style="background-color:#fffaf0;"></div>
+== References ==
+<references/>
 __TOC__
 </StructureSection>