5ikb
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the kainate receptor GluK4 ligand binding domain in complex with kainate== | |
- | + | <StructureSection load='5ikb' size='340' side='right' caption='[[5ikb]], [[Resolution|resolution]] 2.05Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5ikb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IKB FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KAI:3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE'>KAI</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ikb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ikb OCA], [http://pdbe.org/5ikb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ikb RCSB], [http://www.ebi.ac.uk/pdbsum/5ikb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ikb ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/GRIK4_RAT GRIK4_RAT]] Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > glutamate >> AMPA. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Frydenvang, K]] | ||
+ | [[Category: Kastrup, J S]] | ||
+ | [[Category: Kristensen, L B]] | ||
+ | [[Category: Kristensen, O]] | ||
+ | [[Category: High-affinity kainate receptor]] | ||
+ | [[Category: Ion channel]] | ||
+ | [[Category: Ligand binding domain]] | ||
+ | [[Category: Membrane protein]] |
Revision as of 06:51, 10 September 2016
Crystal structure of the kainate receptor GluK4 ligand binding domain in complex with kainate
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