5crl
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Transcription Activator Tn501 MerR in Complex with Mercury (II)== | |
| - | + | <StructureSection load='5crl' size='340' side='right' caption='[[5crl]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5crl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CRL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5crl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5crl OCA], [http://pdbe.org/5crl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5crl RCSB], [http://www.ebi.ac.uk/pdbsum/5crl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5crl ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MERR_PSEAI MERR_PSEAI]] Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chen, H]] | ||
| + | [[Category: Gan, J H]] | ||
[[Category: Wang, D]] | [[Category: Wang, D]] | ||
| - | [[Category: | + | [[Category: Mercury]] |
| - | [[Category: | + | [[Category: Merr]] |
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: P. aeruginosa tn501]] | ||
| + | [[Category: Transcription activator]] | ||
Revision as of 21:01, 10 September 2016
Crystal Structure of the Transcription Activator Tn501 MerR in Complex with Mercury (II)
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