Thioredoxin

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<StructureSection load='1ert' size='350' side='right' caption='Human thioredoxin (PDB entry [[1ert]])' scene=''>
<StructureSection load='1ert' size='350' side='right' caption='Human thioredoxin (PDB entry [[1ert]])' scene=''>
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**[[4oo5]] - hTrx S-nitroso (mutant)<br />
**[[4oo5]] - hTrx S-nitroso (mutant)<br />
**[[1auc]], [[1ert]], [[1eru]] - hTrx<br />
**[[1auc]], [[1ert]], [[1eru]] - hTrx<br />
 +
**[[5dqy]] – hTrx oxidized<br />
**[[1trs]], [[1tru]], [[1trv]], [[1trw]], [[3trx]], [[4trx]] - hTrx - NMR<br />
**[[1trs]], [[1tru]], [[1trv]], [[1trw]], [[3trx]], [[4trx]] - hTrx - NMR<br />
**[[3hxs]] – BfTrx fragment – ''Bacteroides fragilis''<br />
**[[3hxs]] – BfTrx fragment – ''Bacteroides fragilis''<br />
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**[[3f3q]], [[2i9h]] – yTrx-1 – yeast<br />
**[[3f3q]], [[2i9h]] – yTrx-1 – yeast<br />
**[[3f3r]] – yTrx-1 (mutant)<br />
**[[3f3r]] – yTrx-1 (mutant)<br />
-
**[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]] – EcTrx-1 (mutant) <br />
+
**[[2n5a]] – yTrx-1 (mutant) reduced<br />
 +
**[[2n5b]] – yTrx-1 (mutant) oxidized<br />
 +
**[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]], [[4x43]] – EcTrx-1 (mutant) <br />
**[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br />
**[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br />
 +
**[[5e4w]] - EcTrx-1 + signal recognition particle + Albino3<br />
**[[2o8v]] - EcTrx-1 (mutant) + PAPS reductase<br />
**[[2o8v]] - EcTrx-1 (mutant) + PAPS reductase<br />
**[[2ajq]] – EpTrx-1 (mutant)+DNA primer+DNA template+DNA polymerase – Enterobacteria phage T7<br />
**[[2ajq]] – EpTrx-1 (mutant)+DNA primer+DNA template+DNA polymerase – Enterobacteria phage T7<br />
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**[[2ppt]] – Trx-2 – ''Rhodobacter capsulatus''<br />
**[[2ppt]] – Trx-2 – ''Rhodobacter capsulatus''<br />
**[[1thx]] – Trx-2 – Anabaena<br />
**[[1thx]] – Trx-2 – Anabaena<br />
-
**[[3ul3]], [[4o32]] – PfTrx-2
+
**[[3ul3]], [[4o32]] – PfTrx-2<br />
 +
**[[4ruv]] – SaTrx-2 <br />
*Thioredoxin 3
*Thioredoxin 3

Revision as of 09:43, 13 September 2016

Human thioredoxin (PDB entry 1ert)

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3D Structures of Thioredoxin

Updated on 13-September-2016

References

  1. Gleason FK, Holmgren A. Thioredoxin and related proteins in procaryotes. FEMS Microbiol Rev. 1988 Dec;4(4):271-97. PMID:3152490
  2. Sumida Y, Nakashima T, Yoh T, Furutani M, Hirohama A, Kakisaka Y, Nakajima Y, Ishikawa H, Mitsuyoshi H, Okanoue T, Kashima K, Nakamura H, Yodoi J. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol. 2003 Jan;38(1):32-8. PMID:12480557
  3. Burke-Gaffney A, Callister ME, Nakamura H. Thioredoxin: friend or foe in human disease? Trends Pharmacol Sci. 2005 Aug;26(8):398-404. PMID:15990177 doi:http://dx.doi.org/10.1016/j.tips.2005.06.005
  4. Weichsel A, Gasdaska JR, Powis G, Montfort WR. Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure. 1996 Jun 15;4(6):735-51. PMID:8805557
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