5d1z

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'''Unreleased structure'''
 
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The entry 5d1z is ON HOLD until Paper Publication
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==IsdB NEAT1 bound by clone D4-10==
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<StructureSection load='5d1z' size='340' side='right' caption='[[5d1z]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5d1z]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D1Z FirstGlance]. <br>
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Description:
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d1x|5d1x]], [[5diq|5diq]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d1z OCA], [http://pdbe.org/5d1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d1z RCSB], [http://www.ebi.ac.uk/pdbsum/5d1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d1z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ISDB_STAAS ISDB_STAAS]] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Deng, X]]
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[[Category: Germline encoded]]
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[[Category: Immune system]]
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[[Category: Isdb]]
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[[Category: Neat1]]

Revision as of 15:27, 14 September 2016

IsdB NEAT1 bound by clone D4-10

5d1z, resolution 3.17Å

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