5k2b

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'''Unreleased structure'''
 
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The entry 5k2b is ON HOLD until Paper Publication
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==2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data==
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<StructureSection load='5k2b' size='340' side='right' caption='[[5k2b]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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Authors: Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5k2b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K2B FirstGlance]. <br>
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Description: 2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k2a|5k2a]], [[5k2c|5k2c]], [[5k2d|5k2d]]</td></tr>
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[[Category: Liang, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k2b OCA], [http://pdbe.org/5k2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k2b RCSB], [http://www.ebi.ac.uk/pdbsum/5k2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k2b ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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__TOC__
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</StructureSection>
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[[Category: Aquila, A]]
[[Category: Barty, A]]
[[Category: Barty, A]]
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[[Category: Batyuk, A]]
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[[Category: Boutet, S]]
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[[Category: Cherezov, V]]
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[[Category: Fromme, P]]
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[[Category: GPCR, GPCR Network]]
[[Category: Galli, L]]
[[Category: Galli, L]]
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[[Category: Spence, J.C.H]]
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[[Category: Gati, C]]
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[[Category: Hunter, M.S]]
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[[Category: Han, G W]]
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[[Category: Fromme, P]]
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[[Category: Hunter, M S]]
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[[Category: Weierstall, U]]
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[[Category: Ishchenko, A]]
[[Category: Ishchenko, A]]
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[[Category: Stevens, R.C]]
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[[Category: James, D]]
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[[Category: White, T.A]]
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[[Category: Katritch, V]]
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[[Category: Han, G.W]]
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[[Category: Lee, M Y]]
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[[Category: Gati, C]]
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[[Category: Aquila, A]]
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[[Category: Liu, Z.-J]]
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[[Category: Li, C]]
[[Category: Li, C]]
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[[Category: Katritch, V]]
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[[Category: Liang, M]]
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[[Category: Boutet, S]]
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[[Category: Liu, W]]
[[Category: Liu, W]]
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[[Category: Zhao, Y]]
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[[Category: Liu, Z J]]
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[[Category: James, D]]
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[[Category: Nelson, G]]
[[Category: Nelson, G]]
[[Category: Popov, P]]
[[Category: Popov, P]]
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[[Category: Gpcr Network (Gpcr)]]
 
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[[Category: Lee, M.-Y]]
 
[[Category: Pu, M]]
[[Category: Pu, M]]
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[[Category: Cherezov, V]]
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[[Category: Spence, J C.H]]
[[Category: Stauch, B]]
[[Category: Stauch, B]]
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[[Category: Batyuk, A]]
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[[Category: Stevens, R C]]
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[[Category: Weierstall, U]]
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[[Category: White, T A]]
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[[Category: Zhao, Y]]
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[[Category: A2a adenosine receptor]]
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[[Category: Gpcr]]
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[[Category: Gpcr network]]
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[[Category: Membrane protein]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]

Revision as of 13:54, 21 September 2016

2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data

5k2b, resolution 2.50Å

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