5j4z
From Proteopedia
(Difference between revisions)
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| - | ''' | + | {{Large structure}} |
| - | + | ==Architecture of tight respirasome== | |
| - | + | <StructureSection load='5j4z' size='340' side='right' caption='[[5j4z]], [[Resolution|resolution]] 5.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5j4z]] is a 88 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J4Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEA:HEME-A'>HEA</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4z OCA], [http://pdbe.org/5j4z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j4z RCSB], [http://www.ebi.ac.uk/pdbsum/5j4z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4z ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | {{Large structure}} | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/COX2_SHEEP COX2_SHEEP]] Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. [[http://www.uniprot.org/uniprot/W5P2X9_SHEEP W5P2X9_SHEEP]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.[RuleBase:RU004494] [[http://www.uniprot.org/uniprot/COX3_SHEEP COX3_SHEEP]] Subunits I, II and III form the functional core of the enzyme complex. [[http://www.uniprot.org/uniprot/B9VH04_SHEEP B9VH04_SHEEP]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[PIRNR:PIRNR000019] [[http://www.uniprot.org/uniprot/COX1_SHEEP COX1_SHEEP]] Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. [[http://www.uniprot.org/uniprot/CYB_SHEEP CYB_SHEEP]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ovis aries]] | ||
| + | [[Category: Ubiquinol--cytochrome-c reductase]] | ||
[[Category: Fiedorczuk, K]] | [[Category: Fiedorczuk, K]] | ||
| + | [[Category: Letts, J A]] | ||
| + | [[Category: Sazanov, L A]] | ||
| + | [[Category: Electron transport]] | ||
| + | [[Category: Membrane protein complex]] | ||
| + | [[Category: Respirasome]] | ||
| + | [[Category: Supercomplex]] | ||
Revision as of 14:00, 21 September 2016
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Architecture of tight respirasome
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