Trichodiene synthase
From Proteopedia
(Difference between revisions)
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| - | + | <StructureSection load='2q9y' size='340' side='right' caption='Trichodiene synthase complex with diphosphate, competitive inhibitor and Mg+2 ion (green) [[2q9y]]' scene=''> | |
| + | == Function == | ||
| + | '''Trichodiene synthase''' (TCS) catalyzes the conversion of trans,trans-farnesyl diphosphate to trichodiene and diphosphate (PP). TCS belongs to the family of sesquiterpene syntases which cyclize the acyclic farnesyl diphosphate to a sesquiterpene. TCS contains metal ion-binding motif<ref>PMID:7875326</ref>. | ||
| - | + | == Structural highlights == | |
| + | |||
| + | </StructureSection> | ||
== 3D Structures of trichodiene synthase == | == 3D Structures of trichodiene synthase == | ||
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[[1yyr]], [[1yys]], [[1yyt]], [[1yyu]], [[2ael]], [[2aet]] – FsTCS (mutant) + PP + Mg + azabisabolene<br /> | [[1yyr]], [[1yys]], [[1yyt]], [[1yyu]], [[2ael]], [[2aet]] – FsTCS (mutant) + PP + Mg + azabisabolene<br /> | ||
[[2q9y]] – FsTCS + PP + Mg + benzyl triethyl ammonium<br /> | [[2q9y]] – FsTCS + PP + Mg + benzyl triethyl ammonium<br /> | ||
| + | == References == | ||
| + | <references/> | ||
Revision as of 09:20, 22 September 2016
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3D Structures of trichodiene synthase
Updated on 22-September-2016
1jfa – FsTCS – Fusarium sporotrichioides
1kiy, 1yj4, 2ps6 – FsTCS (mutant)
2aek, 2ps4, 2ps7 – FsTCS (mutant) + Mg
1jfg, 2q9z – FsTCS + PP + Mg
1kiz, 1yyq, 2ps5, 2ps8 – FsTCS (mutant) + PP + Mg
1yyr, 1yys, 1yyt, 1yyu, 2ael, 2aet – FsTCS (mutant) + PP + Mg + azabisabolene
2q9y – FsTCS + PP + Mg + benzyl triethyl ammonium
References
- ↑ Bardot O, Clemencet MC, Passilly P, Latruffe N. The analysis of modified peroxisome proliferator responsive elements of the peroxisomal bifunctional enzyme in transfected HepG2 cells reveals two regulatory motifs. FEBS Lett. 1995 Feb 27;360(2):183-6. PMID:7875326
