5gs9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5gs9" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5gs9 is ON HOLD
+
==Crystal structure of CASTOR1-arginine==
-
 
+
<StructureSection load='5gs9' size='340' side='right' caption='[[5gs9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
Authors: Zhang, T., Ding, J.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5gs9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GS9 FirstGlance]. <br>
-
Description: Crystal structure of C1-R
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gs9 OCA], [http://pdbe.org/5gs9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gs9 RCSB], [http://www.ebi.ac.uk/pdbsum/5gs9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gs9 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/GATL3_HUMAN GATL3_HUMAN]] Functions as an intracellular arginine sensor that regulates the TORC1 signaling pathway through the GATOR complex. As a homooligomer or a heterooligomer with GATSL2, directly binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of arginine to GATSL3 disrupts the interaction of GATSL3-containing oligomers with GATOR2 and activates the TORC1 signaling pathway.<ref>PMID:26972053</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Ding, J]]
[[Category: Zhang, T]]
[[Category: Zhang, T]]
-
[[Category: Ding, J]]
+
[[Category: Arginine binding]]
 +
[[Category: Signaling protein]]

Revision as of 17:07, 3 October 2016

Crystal structure of CASTOR1-arginine

5gs9, resolution 2.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5gs9"
Personal tools