5dxy

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'''Unreleased structure'''
 
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The entry 5dxy is ON HOLD until Paper Publication
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==Crystal structure of Dbr2==
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<StructureSection load='5dxy' size='340' side='right' caption='[[5dxy]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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Authors: Li, L., Chen, T.T., Xu, Y.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5dxy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DXY FirstGlance]. <br>
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Description: Crystal structure of Dbr2
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5J8:[[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl+hydrogen+phosphate'>5J8</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dxx|5dxx]], [[5dy2|5dy2]], [[5dy3|5dy3]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Artemisinic_aldehyde_Delta(11(13))_reductase Artemisinic aldehyde Delta(11(13)) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.92 1.3.1.92] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dxy OCA], [http://pdbe.org/5dxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dxy RCSB], [http://www.ebi.ac.uk/pdbsum/5dxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dxy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN]] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Chen, T T]]
[[Category: Li, L]]
[[Category: Li, L]]
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[[Category: Chen, T.T]]
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[[Category: Xu, Y C]]
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[[Category: Xu, Y.C]]
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[[Category: Dbr2]]
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[[Category: Oxidoreductase]]

Revision as of 21:23, 5 October 2016

Crystal structure of Dbr2

5dxy, resolution 1.77Å

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