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5kas
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) with phosphocholine== | |
| - | + | <StructureSection load='5kas' size='340' side='right' caption='[[5kas]], [[Resolution|resolution]] 1.62Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5kas]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KAS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kar|5kar]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kas OCA], [http://pdbe.org/5kas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kas RCSB], [http://www.ebi.ac.uk/pdbsum/5kas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kas ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ASM3B_MOUSE ASM3B_MOUSE]] Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (PubMed:26095358).<ref>PMID:26095358</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gorelik, A]] | ||
| + | [[Category: Heinz, L X]] | ||
| + | [[Category: Illes, K]] | ||
| + | [[Category: Nagar, B]] | ||
| + | [[Category: Superti-Furga, G]] | ||
| + | [[Category: Extracellular]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Phosphocholine]] | ||
| + | [[Category: Phosphoesterase]] | ||
Revision as of 21:32, 5 October 2016
Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) with phosphocholine
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