User:Wally Novak/Sandbox Miller

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<Structure load='1X9N' size='350' frame='true' align='right' caption='Human DNA Ligase I' scene='Protein residues 262-919 encircling nicked DNA' />==Your Heading Here (maybe something like 'Structure')== 2
<Structure load='1X9N' size='350' frame='true' align='right' caption='Human DNA Ligase I' scene='Protein residues 262-919 encircling nicked DNA' />==Your Heading Here (maybe something like 'Structure')== 2
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DNA ligases are a group of proteins responsible for the joining DNA fragments which arise from various cellular events: ligating Okazaki fragments from replication, various repair mechanisms, and recombination. <ref>DOI:10.1146/annurev.biochem.77.061306.123941;DOI:10.1074/jbc.R900017200</ref> The ligation proceeds via a three step process uniting the 3'-OH to the 5'-phosphate with an ATP or NAD^+ cofactor. <ref>DOI:10.1146/annurev.biochem.77.061306.123941;DOI:10.1074/jbc.R900017200;DOI:10.1021/cr040498d</ref>
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DNA ligases are a group of proteins responsible for the joining DNA fragments which arise from various cellular events: ligating Okazaki fragments from replication, various repair mechanisms, and recombination. <ref>DOI:10.1146/annurev.biochem.77.061306.123941,DOI:10.1074/jbc.R900017200</ref> The ligation proceeds via a three step process uniting the 3'-OH to the 5'-phosphate with an ATP or NAD^+ cofactor. <ref>DOI:10.1146/annurev.biochem.77.061306.123941,DOI:10.1074/jbc.R900017200,DOI:10.1021/cr040498d</ref>
== Structural Domains ==
== Structural Domains ==

Revision as of 23:18, 7 October 2016

Human DNA Ligase I

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==Your Heading Here (maybe something like 'Structure')== 2

DNA ligases are a group of proteins responsible for the joining DNA fragments which arise from various cellular events: ligating Okazaki fragments from replication, various repair mechanisms, and recombination. [1] The ligation proceeds via a three step process uniting the 3'-OH to the 5'-phosphate with an ATP or NAD^+ cofactor. [2]

Contents

Structural Domains

Ligating Mechanism

Okazaki Fragments and Replication

DNA Repair Involvement

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>

References

  1. ↑ doi: https://dx.doi.org/10.1146/annurev.biochem.77.061306.123941,DOI
  2. ↑ doi: https://dx.doi.org/10.1146/annurev.biochem.77.061306.123941,DOI

[1] to the rescue.

Proteopedia Page Contributors and Editors (what is this?)

Wally Novak

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