User:Wally Novak/Sandbox Hicks
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
== Proliferating Cell Nuclear Antigen == | == Proliferating Cell Nuclear Antigen == | ||
| - | <StructureSection load='1plq' size='340' side='right' caption='Crystal Structure of Proliferating Cell Nuclear Antigen Found in | + | <StructureSection load='1plq' size='340' side='right' caption='Crystal Structure of Proliferating Cell Nuclear Antigen Found in S. cervisiae' scene=''> |
| - | + | ||
Proliferating Cell Nuclear Antigen (PCNA) is a cyclic trimer involved with a number of cellular processes. In general, PCNA works as a sliding ring-shaped clamp that anchors replisome proteins to double stranded DNA to prevent dissociation. In processive elongation of the leading and lagging strands of DNA, PCNA assembly is coupled with ATP hydrolysis by Replication Factor C (RFC) onto a primed DNA template. PCNA then associates with DNA polymerase δ (pol δ) creating a holoenzyme such that pol δ synthesizes new DNA strands without dissociating from the DNA template. | Proliferating Cell Nuclear Antigen (PCNA) is a cyclic trimer involved with a number of cellular processes. In general, PCNA works as a sliding ring-shaped clamp that anchors replisome proteins to double stranded DNA to prevent dissociation. In processive elongation of the leading and lagging strands of DNA, PCNA assembly is coupled with ATP hydrolysis by Replication Factor C (RFC) onto a primed DNA template. PCNA then associates with DNA polymerase δ (pol δ) creating a holoenzyme such that pol δ synthesizes new DNA strands without dissociating from the DNA template. | ||
| - | == | + | == Structural Highlights == |
| - | + | ||
| - | == | + | |
| + | == Interaction with DNA == | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Revision as of 08:36, 11 October 2016
Proliferating Cell Nuclear Antigen
| |||||||||||
