5e68

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'''Unreleased structure'''
 
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The entry 5e68 is ON HOLD until Oct 09 2017
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==High resolution crystal structure of LuxS - Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms==
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<StructureSection load='5e68' size='340' side='right' caption='[[5e68]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
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Authors: Perumal, P., Raina, R., Arockiasamy, A., SundaraBaalaji, N.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5e68]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E68 FirstGlance]. <br>
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Description: High resolution crystal structure of LuxS -Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1joe|1joe]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/S-ribosylhomocysteine_lyase S-ribosylhomocysteine lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.21 4.4.1.21] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e68 OCA], [http://pdbe.org/5e68 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e68 RCSB], [http://www.ebi.ac.uk/pdbsum/5e68 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e68 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LUXS_SALTI LUXS_SALTI]] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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__TOC__
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</StructureSection>
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[[Category: S-ribosylhomocysteine lyase]]
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[[Category: Arockiasamy, A]]
[[Category: Perumal, P]]
[[Category: Perumal, P]]
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[[Category: Sundarabaalaji, N]]
 
[[Category: Raina, R]]
[[Category: Raina, R]]
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[[Category: Arockiasamy, A]]
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[[Category: SundaraBaalaji, N]]
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[[Category: Lux]]
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[[Category: Lyase]]
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[[Category: Quroum sensing protein]]
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[[Category: Salmonella typhi]]

Revision as of 17:37, 19 October 2016

High resolution crystal structure of LuxS - Quorum sensor molecular complex from Salmonella typhi at 1.58 Angstroms

5e68, resolution 1.58Å

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