5fdx

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m (Protected "5fdx" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5fdx is ON HOLD until Paper Publication
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==Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.==
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<StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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Authors: BARTUAL, S.G., PINKAS, D.M., WANG, Z., DING, K., Mahajan, P., KUPINSKA, K., Mukhopadhyay, S., Strain-Damerell, C., Chalk, R., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., VON DELFT, F., Arrowsmith, C.H., Edwards, A.M., BOUNTRA, C., BULLOCK, A., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
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Description: Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
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[[Category: Bullock, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Arrowsmith, C H]]
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[[Category: BARTUAL, S G]]
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[[Category: BOUNTRA, C]]
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[[Category: BULLOCK, A]]
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[[Category: Borkowska, O]]
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[[Category: Burgess-Brown, N]]
[[Category: Chaikuad, A]]
[[Category: Chaikuad, A]]
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[[Category: Sorell, F]]
 
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[[Category: Burgess-Brown, N]]
 
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[[Category: Borkowska, O]]
 
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[[Category: Pinkas, D.M]]
 
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[[Category: Newman, J]]
 
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[[Category: Mukhopadhyay, S]]
 
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[[Category: Ding, K]]
 
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[[Category: Wang, Z]]
 
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[[Category: Bountra, C]]
 
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[[Category: Bartual, S.G]]
 
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[[Category: Kupinska, K]]
 
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[[Category: Arrowsmith, C.H]]
 
[[Category: Chalk, R]]
[[Category: Chalk, R]]
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[[Category: Williams, E]]
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[[Category: DELFT, F VON]]
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[[Category: DING, K]]
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[[Category: Edwards, A M]]
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[[Category: KUPINSKA, K]]
[[Category: Kopec, J]]
[[Category: Kopec, J]]
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[[Category: Von Delft, F]]
 
[[Category: Mahajan, P]]
[[Category: Mahajan, P]]
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[[Category: Edwards, A.M]]
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[[Category: Mukhopadhyay, S]]
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[[Category: Newman, J]]
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[[Category: PINKAS, D M]]
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[[Category: Structural genomic]]
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[[Category: Sorell, F]]
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[[Category: Strain-Damerell, C]]
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[[Category: Tallant, C]]
[[Category: Talon, R]]
[[Category: Talon, R]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: WANG, Z]]
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[[Category: Tallant, C]]
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[[Category: Williams, E]]
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[[Category: Strain-Damerell, C]]
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[[Category: Ddr1 kinase]]
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[[Category: Inhibitor]]
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[[Category: Psi-biology]]
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[[Category: Sgc]]
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[[Category: Transferase]]

Revision as of 18:41, 26 October 2016

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

5fdx, resolution 2.65Å

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