5jfg

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'''Unreleased structure'''
 
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The entry 5jfg is ON HOLD
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==Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA==
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<StructureSection load='5jfg' size='340' side='right' caption='[[5jfg]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5jfg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JFG FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jfg OCA], [http://pdbe.org/5jfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jfg RCSB], [http://www.ebi.ac.uk/pdbsum/5jfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jfg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
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__TOC__
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</StructureSection>
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[[Category: Abell, C]]
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[[Category: Blundell, T L]]
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[[Category: Fischer, G]]
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[[Category: Hyvonen, M]]
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[[Category: Marsh, M]]
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[[Category: Morgan, M]]
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[[Category: Moschetti, T]]
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[[Category: Ng, H]]
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[[Category: Scott, D]]
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[[Category: Sharpe, T]]
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[[Category: Skidmore, J]]
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[[Category: Venkitaraman, A]]
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[[Category: Dna repair]]
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[[Category: Fragment based drug design]]
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[[Category: Humanisation]]
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[[Category: Hydrolase]]

Revision as of 18:46, 26 October 2016

Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA

5jfg, resolution 1.77Å

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