5t48
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact== | |
| - | + | <StructureSection load='5t48' size='340' side='right' caption='[[5t48]], [[Resolution|resolution]] 2.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5t48]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T48 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGP:7-METHYL-GUANOSINE-5-TRIPHOSPHATE'>MGP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t48 OCA], [http://pdbe.org/5t48 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t48 RCSB], [http://www.ebi.ac.uk/pdbsum/5t48 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t48 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IF4E_DROME IF4E_DROME]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.<ref>PMID:8663200</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chung, M Y]] | ||
| + | [[Category: Gruener, S]] | ||
| + | [[Category: Igreja, C]] | ||
| + | [[Category: Izaurralde, E]] | ||
| + | [[Category: Peter, D]] | ||
| + | [[Category: Valkov, E]] | ||
| + | [[Category: Weber, R]] | ||
| + | [[Category: Weichenrieder, O]] | ||
| + | [[Category: Wohlbold, L]] | ||
| + | [[Category: 4e-binding protein]] | ||
| + | [[Category: Cap binding protein]] | ||
| + | [[Category: Eif4f]] | ||
| + | [[Category: Gene regulation]] | ||
| + | [[Category: Translation]] | ||
| + | [[Category: Translation initiation]] | ||
Revision as of 18:50, 26 October 2016
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
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