Major capsid protein L1
From Proteopedia
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== Introduction== | == Introduction== | ||
| - | Gardasil 9 is a recombinant vaccine for the human papillomavirus and protects from the 9 most common forms that are known to cause the majority of HPV-related diseases and cancer. These types are 6, 11, 16, 18, 31, 33, 45, 52, and 58. HPVs are the causative agents of human neoplasia such as warts and cancers <ref>DOI 10.1016/j.antiviral.2016.03.016</ref>. The HPV vaccine is recommended for children ages 11 to 12 and is intended for females ages 9-25 and protects against cervical cancer, vulvar and vaginal cancer, anal cancer, and genital warts. The vaccine is also intended for males ages 9-26 and protects against anal cancer and genital warts <ref>https://www.gardasil9.com</ref>. Gardasil vaccine is made up of proteins that resemble the ones on the outside of an actual human papillomavirust <ref name="aus">http://www.hpvvaccine.org.au/the-hpv-vaccine/how-does-it-work.aspx</ref>.The main ingredient in Gardasil 9 is the | + | Gardasil 9 is a recombinant vaccine for the human papillomavirus and protects from the 9 most common forms that are known to cause the majority of HPV-related diseases and cancer. These types are 6, 11, 16, 18, 31, 33, 45, 52, and 58. HPVs are the causative agents of human neoplasia such as warts and cancers <ref>DOI 10.1016/j.antiviral.2016.03.016</ref>. The HPV vaccine is recommended for children ages 11 to 12 and is intended for females ages 9-25 and protects against cervical cancer, vulvar and vaginal cancer, anal cancer, and genital warts. The vaccine is also intended for males ages 9-26 and protects against anal cancer and genital warts <ref>https://www.gardasil9.com</ref>. Gardasil vaccine is made up of proteins that resemble the ones on the outside of an actual human papillomavirust <ref name="aus">http://www.hpvvaccine.org.au/the-hpv-vaccine/how-does-it-work.aspx</ref>.The main ingredient in Gardasil 9 is the<scene name='74/746002/L1_pentamer_structure/2'>L1 major capsid protein</scene> <ref name="L1">https://www.medicines.org.uk/emc/medicine/19016</ref>. |
== Function == | == Function == | ||
Revision as of 21:52, 15 November 2016
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References
- ↑ Zhai L, Tumban E. Gardasil-9: A global survey of projected efficacy. Antiviral Res. 2016 Jun;130:101-9. doi: 10.1016/j.antiviral.2016.03.016. Epub, 2016 Apr 1. PMID:27040313 doi:http://dx.doi.org/10.1016/j.antiviral.2016.03.016
- ↑ https://www.gardasil9.com
- ↑ 3.0 3.1 http://www.hpvvaccine.org.au/the-hpv-vaccine/how-does-it-work.aspx
- ↑ 4.0 4.1 https://www.medicines.org.uk/emc/medicine/19016
- ↑ doi: https://dx.doi.org/10.1128/JVI.77.8.4818-4826.2003
- ↑ http://www.uniprot.org/uniprot/P03101
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Morgan Smith, Michal Harel, Jessica Troutman., Maximillia Jackson., Jaime Prilusky
