Mitogen-activated protein kinase

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*MAPK1
*MAPK1
**[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br />
**[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br />
-
**[[3i5z]], [[3i60]], [[2e14]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]] – hMAPK1+inhibitor - human<br />
+
**[[3i5z]], [[3i60]], [[3w55]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]] – hMAPK1+inhibitor - human<br />
**[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br />
**[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br />
**[[3tei]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br />
**[[3tei]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br />
Line 31: Line 31:
**[[4fmq]] – hMAPK1 + MAPK docking peptide<br />
**[[4fmq]] – hMAPK1 + MAPK docking peptide<br />
**[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br />
**[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br />
-
**[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]], [[3qyi]] - rMAPK1+inhibitor – rat<br />
+
**[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]] - rMAPK1+inhibitor – rat<br />
**[[1erk]] - rMAPK1<br />
**[[1erk]] - rMAPK1<br />
**[[1gol]], [[3r63]] - rMAPK1 (mutant)<br />
**[[1gol]], [[3r63]] - rMAPK1 (mutant)<br />
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*MAPK10
*MAPK10
-
**[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[1pmq]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]] – hMAPK10+inhibitor<br />
+
**[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[4z9l]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]] – hMAPK10+inhibitor<br />
**[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br />
**[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br />
**[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br />
**[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br />
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*MAPK13
*MAPK13
-
**[[3coi]], [[4exu]] – hMAPK13<br />
+
**[[3coi]], [[4yno]] – hMAPK13<br />
**[[4eyj]], [[4eym]] - hMAPK13 +inhibitor<br />
**[[4eyj]], [[4eym]] - hMAPK13 +inhibitor<br />

Revision as of 11:09, 17 November 2016

Human MAPK1 complex with inhibitor and sulfate (PDB entry 2ojg)

Drag the structure with the mouse to rotate

3D Structures of Mitogen-activated protein kinase

Updated on 17-November-2016

References

  1. ↑ Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol. 1997 Apr;9(2):180-6. PMID:9069255
  2. ↑ Aronov AM, Baker C, Bemis GW, Cao J, Chen G, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Martinez-Botella G, Namchuk MN, Straub J, Tang Q, Xie X. Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors. J Med Chem. 2007 Mar 22;50(6):1280-7. Epub 2007 Feb 15. PMID:17300186 doi:http://dx.doi.org/10.1021/jm061381f

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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