This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Mitogen-activated protein kinase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 25: Line 25:
*MAPK1
*MAPK1
**[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br />
**[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br />
-
**[[3i5z]], [[3i60]], [[2e14]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]] – hMAPK1+inhibitor - human<br />
+
**[[3i5z]], [[3i60]], [[3w55]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]] – hMAPK1+inhibitor - human<br />
**[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br />
**[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br />
**[[3tei]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br />
**[[3tei]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br />
Line 31: Line 31:
**[[4fmq]] – hMAPK1 + MAPK docking peptide<br />
**[[4fmq]] – hMAPK1 + MAPK docking peptide<br />
**[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br />
**[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br />
-
**[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]], [[3qyi]] - rMAPK1+inhibitor – rat<br />
+
**[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]] - rMAPK1+inhibitor – rat<br />
**[[1erk]] - rMAPK1<br />
**[[1erk]] - rMAPK1<br />
**[[1gol]], [[3r63]] - rMAPK1 (mutant)<br />
**[[1gol]], [[3r63]] - rMAPK1 (mutant)<br />
Line 88: Line 88:
*MAPK10
*MAPK10
-
**[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[1pmq]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]] – hMAPK10+inhibitor<br />
+
**[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[4z9l]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]] – hMAPK10+inhibitor<br />
**[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br />
**[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br />
**[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br />
**[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br />
Line 103: Line 103:
*MAPK13
*MAPK13
-
**[[3coi]], [[4exu]] – hMAPK13<br />
+
**[[3coi]], [[4yno]] – hMAPK13<br />
**[[4eyj]], [[4eym]] - hMAPK13 +inhibitor<br />
**[[4eyj]], [[4eym]] - hMAPK13 +inhibitor<br />

Revision as of 11:09, 17 November 2016

Human MAPK1 complex with inhibitor and sulfate (PDB entry 2ojg)

Drag the structure with the mouse to rotate

3D Structures of Mitogen-activated protein kinase

Updated on 17-November-2016

References

  1. ↑ Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol. 1997 Apr;9(2):180-6. PMID:9069255
  2. ↑ Aronov AM, Baker C, Bemis GW, Cao J, Chen G, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Martinez-Botella G, Namchuk MN, Straub J, Tang Q, Xie X. Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors. J Med Chem. 2007 Mar 22;50(6):1280-7. Epub 2007 Feb 15. PMID:17300186 doi:http://dx.doi.org/10.1021/jm061381f

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Mitogen-activated_protein_kinase"
Personal tools