Nucleoprotein
From Proteopedia
(Difference between revisions)
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| - | {{STRUCTURE_3mx2| PDB=3mx2 | SIZE= | + | {{STRUCTURE_3mx2| PDB=3mx2 | SIZE=350| SCENE= |right|CAPTION=Nucleoprotein from Lassa virus trimer complex with TTP (stick model) and Zn+2 ions (grey) [[3mx2]] }} |
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**[[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br /> | **[[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br /> | ||
| - | **[[ | + | **[[4wzj]] – h-snRNP U4 core domain<br /> |
**[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br /> | **[[3p49]] - h-snRNP A RRM + glycine riboswitch RNA<br /> | ||
**[[3iwn]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br /> | **[[3iwn]] - h-snRNP U1 A RRM (mutant) + riboswitch RNA<br /> | ||
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**[[3cw1]] - h-snRNP U1 in spliceosome<br /> | **[[3cw1]] - h-snRNP U1 in spliceosome<br /> | ||
**[[2ozb]], [[3siu]], [[3siv]] - h-snRNP U4/U6 + NHP2-like protein + RNA<br /> | **[[2ozb]], [[3siu]], [[3siv]] - h-snRNP U4/U6 + NHP2-like protein + RNA<br /> | ||
| - | **[[3s6n]], [[ | + | **[[3s6n]], [[4v98]], [[4f7u]] - h-snRNP 8S assembly<br /> |
**[[4m77]], [[4m78]], [[4m7a]], [[4m7d]] - h-snRNP LSM8 assembly<br /> | **[[4m77]], [[4m78]], [[4m7a]], [[4m7d]] - h-snRNP LSM8 assembly<br /> | ||
**[[2bn5]] - Dm-snRNP U1 70kDa + PSI B box – NMR<br /> | **[[2bn5]] - Dm-snRNP U1 70kDa + PSI B box – NMR<br /> | ||
Revision as of 11:23, 17 November 2016
Nucleoproteins (NP) are proteins associated with DNA or RNA[1]. NPs which contain RNA are called ribonucleoproteins (RNPs). The NP RNA-recognition motif is named RRM. The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome[2]. The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA[3].
For details on heterogenous nuclear ribonucleoproteins see HnRNP A1.
For homology model and multiple sequence alignment see User:Michael Strong/H1N1/NP and User:Michael Strong/H1N1/NP/MSA.
3D Structures of Nucleoprotein
Updated on 17-November-2016
References
- ↑ Echols H. Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination. J Biol Chem. 1990 Sep 5;265(25):14697-700. PMID:2203758
- ↑ Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 2004 May;14(5):226-32. PMID:15130578 doi:http://dx.doi.org/10.1016/j.tcb.2004.03.010
- ↑ He Y, Smith R. Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B. Cell Mol Life Sci. 2009 Apr;66(7):1239-56. doi: 10.1007/s00018-008-8532-1. PMID:19099192 doi:http://dx.doi.org/10.1007/s00018-008-8532-1
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