This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.




GTP-binding protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 252: Line 252:
*'''Small GTPase h-Ras''' see [[GTPase HRas]]
*'''Small GTPase h-Ras''' see [[GTPase HRas]]
-
*'''Heterotrimeric G protein'''
+
*'''Heterotrimeric G protein see [[Transducin]]'''
-
 
+
-
*GNBP α subunit
+
-
 
+
-
**[[1gia]], [[1gil]] – rGNBP + GSP – rat <br />
+
-
**[[1gfi]], [[1gdd]], [[1bof]] – rGNBP + GDP <br />
+
-
**[[1cip]], [[1svs]] – rGNBP + GNP <br />
+
-
**[[1git]], [[1as3]], [[1svk]], [[3d7m]], [[2zjy]], [[2zjz]], [[3ffb]], [[4n0e]] – rGNBP (mutant) + GDP <br />
+
-
**[[1bh2]], [[3ffa]] – rGNBP (mutant) + GSP <br />
+
-
**[[3ums]], [[3umr]] – hGNBP (mutant) + GDP - human <br />
+
-
**[[1as0]], [[4n0d]] – rGNBP (mutant) + GTPγS <br />
+
-
**[[1as2]] – rGNBP (mutant) + GDP + Pi<br />
+
-
**[[3v00]] – rGNBP/bGNBP (mutant) + GDP <br />
+
-
**[[2xtz]] - GNBP + GDP derivative – ''Arabidopsis thaliana'' <br />
+
-
 
+
-
*GNBP α subunit complex with protein
+
-
 
+
-
**[[1agr]] – rGNBP + GDP + regulator of G protein signalling<br />
+
-
**[[1kjy]], [[2gtp]], [[2ik8]], [[2om2]], [[4g5q]], [[2ihb]], [[2ode]], [[2v4z]], [[3onw]] – hGNBP + GDP + regulator of G protein signaling <br />
+
-
**[[2om2]] – hGNBP (mutant) + GDP + regulator of G protein signaling <br />
+
-
**[[2xns]] – hGNBP + GDP + regulator of G protein signaling peptide<br />
+
-
**[[3qi2]] – hGNBP (mutant) + GDP + regulator of G protein signaling peptide<br />
+
-
**[[4g5o]], [[4g5r]], [[4g5s]] – hGNBP (mutant) + GDP + G protein signaling modulator<br />
+
-
**[[1shz]] – rGNBP/mGNBP + GDP + ρ guanine nucleotide exchange factor<br />
+
-
**[[1y3a]] – rGNBP + GDP + Kb752 peptide<br />
+
-
**[[3qe0]] – hGNBP (mutant) + GDP + Kb752 peptide<br />
+
-
**[[2g83]] – hGNBP + GDP + Kb1753 peptide<br />
+
-
**[[4g5o]], [[4g5r]], [[4g5s]] – hGNBP (mutant) + GDP + G protein signaling modulator<br />
+
-
**[[1cjk]], [[1cjt]], [[1cju]], [[1cjv]], [[1cs4]], [[1cul]] – hGNBP (mutant) + GTP derivative + adenylate cyclase<br />
+
-
**[[1u0h]] – hGNBP + GTP derivative + adenylate cyclase<br />
+
-
**[[2gvd]], [[2gvz]], [[3maa]] – bGNBP + ATP derivative + adenylate cyclase<br />
+
-
**[[3g82]] – bGNBP + ITP derivative + adenylate cyclase<br />
+
-
**[[3c14]], [[3c15]], [[3c16]] – bGNBP + PPi + adenylate cyclase<br />
+
-
**[[1tl7]] – bGNBP (mutant) + GTP derivative + adenylate cyclase<br />
+
-
**[[2rgn]] – mGNBP + RHOA exchange factor + transforming protein RHOA – mouse<br />
+
-
**[[3cx8]] – mGNBP + GTP + RHOA exchange factor <br />
+
-
**[[3c7k]] – mGNBP + GDP + regulator of G protein signaling <br />
+
-
**[[4ekc]], [[4ekd]] – mGNBP (mutant) + GDP + regulator of G protein signaling <br />
+
-
**[[3ohm]], [[4gnk]] – mGNBP + GDP + phospholipase C <br />
+
-
 
+
-
*GNBP β subunit
+
-
 
+
-
**[[2pbi]] – mGNBP + regulator of G protein signaling <br />
+
-
 
+
-
*GNBP β+γ subunits
+
-
 
+
-
**[[1omw]] – bGNBP + G protein coupled receptor kinase <br />
+
-
**[[3v5w]] – bGNBP (mutant) + G protein coupled receptor kinase <br />
+
-
**[[1xhm]] – bGNBP + peptide<br />
+
-
**[[3krw]], [[3krx]] – bGNBP + balanol + β-adrenergic receptor kinase<br />
+
-
**[[3psc]], [[3pvu]], [[3pvw]], [[4mk0]] – bGNBP + β-adrenergic receptor kinase<br />
+
-
**[[3uzs]] – bGNBP + RNA + β-adrenergic receptor kinase<br />
+
-
**[[4kfm]] – hGNBP + inward rectifier K+ channel<br />
+
-
 
+
-
*GNBP α+β+γ subunits
+
-
 
+
-
**[[1gg2]], [[1gp2]] – rGNBP (mutant) + GDP <br />
+
-
**[[1shz]] – rGNBP/mGNBP (mutant)+ GDP + inhibitor<br />
+
-
**[[2bcj]] – bGNBP (mutant) + G protein coupled receptor kinase <br />
+
-
**[[3sn6]] – bGNBP (mutant) + lysozyme <br />
+
}}
}}

Revision as of 07:54, 28 November 2016

E. coli small GTP-binding protein ERA complex with GDP and sulfate (PDB code 3ieu)

Drag the structure with the mouse to rotate

3D Structures of GTP-binding protein

Updated on 28-November-2016

See Also

References

  1. Preininger AM, Hamm HE. G protein signaling: insights from new structures. Sci STKE. 2004 Jan 27;2004(218):re3. PMID:14762218 doi:http://dx.doi.org/10.1126/stke.2182004re3
  2. Takai Y, Sasaki T, Matozaki T. Small GTP-binding proteins. Physiol Rev. 2001 Jan;81(1):153-208. PMID:11152757
  3. Lania A, Mantovani G, Spada A. G protein mutations in endocrine diseases. Eur J Endocrinol. 2001 Nov;145(5):543-59. PMID:11720871
  4. Tu C, Zhou X, Tropea JE, Austin BP, Waugh DS, Court DL, Ji X. Structure of ERA in complex with the 3' end of 16S rRNA: implications for ribosome biogenesis. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14843-8. Epub 2009 Aug 17. PMID:19706445
Personal tools