Ubiquitin conjugating enzyme

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== Structural highlights ==
== Structural highlights ==
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The active site of Ubc contains a cysteine residue. The ubiquitin surface which interacts with Ubc contains a K11-linkage formation<ref>PMID:21396940</ref>.
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The active site of Ubc contains a cysteine residue. The <scene name='55/551219/Cv/2'>ubiquitin surface which interacts with Ubc</scene><ref>PMID:21396940</ref>.
</StructureSection>
</StructureSection>

Revision as of 08:55, 5 December 2016

Structure of human ubiquitin conjugating enzyme E2 (green) complex with ubiquitin (deepskyblue) (PDB entry 3ptf)

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3D Structures of ubiquitin conjugating enzyme

Updated on 05-December-2016

References

  1. Markson G, Kiel C, Hyde R, Brown S, Charalabous P, Bremm A, Semple J, Woodsmith J, Duley S, Salehi-Ashtiani K, Vidal M, Komander D, Serrano L, Lehner P, Sanderson CM. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res. 2009 Oct;19(10):1905-11. Epub 2009 Jun 23. PMID:19549727 doi:http://dx.doi.org/gr.093963.109
  2. Bosanac I, Phu L, Pan B, Zilberleyb I, Maurer B, Dixit VM, Hymowitz SG, Kirkpatrick DS. Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A. J Mol Biol. 2011 May 6;408(3):420-31. Epub 2011 Mar 10. PMID:21396940 doi:10.1016/j.jmb.2011.03.011

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Michal Harel, Alexander Berchansky, David A Taves

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