1q7o
From Proteopedia
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|PDB= 1q7o |SIZE=350|CAPTION= <scene name='initialview01'>1q7o</scene> | |PDB= 1q7o |SIZE=350|CAPTION= <scene name='initialview01'>1q7o</scene> | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=EHP:3-HYDROXYPHENYLALANINE'>EHP</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=MTY:META-TYROSINE'>MTY</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q7o OCA], [http://www.ebi.ac.uk/pdbsum/1q7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1q7o RCSB]</span> | ||
}} | }} | ||
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[[Category: mlf]] | [[Category: mlf]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:09:56 2008'' |
Revision as of 20:09, 30 March 2008
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| Ligands: | , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Determination of f-MLF-OH Peptide Structure with solid-state magic-angle spinning NMR Spectroscopy
Overview
The three-dimensional structure of the chemotactic peptide N-formyl-l-Met-l-Leu-l-Phe-OH was determined by using solid-state NMR (SSNMR). The set of SSNMR data consisted of 16 (13)C-(15)N distances and 18 torsion angle constraints (on 10 angles), recorded from uniformly (13)C,(15)N- and (15)N-labeled samples. The peptide's structure was calculated by means of simulated annealing and a newly developed protocol that ensures that all of conformational space, consistent with the structural constraints, is searched completely. The result is a high-quality structure of a molecule that has thus far not been amenable to single-crystal diffraction studies. The extensions of the SSNMR techniques and computational methods to larger systems appear promising.
About this Structure
1Q7O is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy., Rienstra CM, Tucker-Kellogg L, Jaroniec CP, Hohwy M, Reif B, McMahon MT, Tidor B, Lozano-Perez T, Griffin RG, Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10260-5. Epub 2002 Jul 29. PMID:12149447
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