3lt2

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==Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T3==
==Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T3==
<StructureSection load='3lt2' size='340' side='right' caption='[[3lt2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3lt2' size='340' side='right' caption='[[3lt2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lt2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LT2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lt2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LT2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FT3:2-(2,4-DICHLOROPHENOXY)-5-(HYDROXYMETHYL)PHENOL'>FT3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FT3:2-(2,4-DICHLOROPHENOXY)-5-(HYDROXYMETHYL)PHENOL'>FT3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1uh5|1uh5]], [[1v35|1v35]], [[2oos|2oos]], [[2ol4|2ol4]], [[1zxl|1zxl]], [[1zsn|1zsn]], [[3lsy|3lsy]], [[3lt0|3lt0]], [[3lt1|3lt1]], [[3lt4|3lt4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1uh5|1uh5]], [[1v35|1v35]], [[2oos|2oos]], [[2ol4|2ol4]], [[1zxl|1zxl]], [[1zsn|1zsn]], [[3lsy|3lsy]], [[3lt0|3lt0]], [[3lt1|3lt1]], [[3lt4|3lt4]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lt2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lt2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt2 OCA], [http://pdbe.org/3lt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lt2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lt2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lt2 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lt2 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3lt2" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Plasmodium falciparum]]
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[[Category: Plafa]]
[[Category: Bhargav, S P]]
[[Category: Bhargav, S P]]
[[Category: Maity, K]]
[[Category: Maity, K]]

Revision as of 20:20, 9 December 2016

Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T3

3lt2, resolution 2.50Å

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