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3k39
From Proteopedia
(Difference between revisions)
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==Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Peramivir== | ==Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Peramivir== | ||
<StructureSection load='3k39' size='340' side='right' caption='[[3k39]], [[Resolution|resolution]] 2.54Å' scene=''> | <StructureSection load='3k39' size='340' side='right' caption='[[3k39]], [[Resolution|resolution]] 2.54Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3k39]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3k39]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_b_virus_(b/perth/211/2001) Influenza b virus (b/perth/211/2001)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K39 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K39 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCZ:3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC+ACID'>BCZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=YT3:YTTRIUM+(III)+ION'>YT3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCZ:3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC+ACID'>BCZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=YT3:YTTRIUM+(III)+ION'>YT3</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3k36|3k36]], [[3k37|3k37]], [[3k38|3k38]], [[3k3a|3k3a]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3k36|3k36]], [[3k37|3k37]], [[3k38|3k38]], [[3k3a|3k3a]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k39 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k39 RCSB], [http://www.ebi.ac.uk/pdbsum/3k39 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k39 OCA], [http://pdbe.org/3k39 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k39 RCSB], [http://www.ebi.ac.uk/pdbsum/3k39 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k39 ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3k39" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
| - | [[Category: Influenza b virus]] | ||
[[Category: McKimm-Breschkin, J L]] | [[Category: McKimm-Breschkin, J L]] | ||
[[Category: Oakley, A J]] | [[Category: Oakley, A J]] | ||
Revision as of 20:22, 9 December 2016
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Peramivir
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Categories: Exo-alpha-sialidase | McKimm-Breschkin, J L | Oakley, A J | 229614-55-5 | 229615-12-7 | Bcx-1812 | Biocryst | Cell membrane | Glycosidase | Hydrolase | Influenza | Membrane | Mutation | Neuraminidase | Peramivir | Resistance | Rwj-270201 | Transmembrane | Virion
