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3o2w

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==Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog==
==Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog==
<StructureSection load='3o2w' size='340' side='right' caption='[[3o2w]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='3o2w' size='340' side='right' caption='[[3o2w]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3o2w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O2W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3o2w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O2W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=O2W:METHYL+({[(3AR,4R,7R,7AR)-2-(4-AMINOPHENYL)-1,3-DIOXOOCTAHYDRO-4H-4,7-ETHANOISOINDOL-4-YL]CARBAMOYL}OXY)ACETATE'>O2W</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=O2W:METHYL+({[(3AR,4R,7R,7AR)-2-(4-AMINOPHENYL)-1,3-DIOXOOCTAHYDRO-4H-4,7-ETHANOISOINDOL-4-YL]CARBAMOYL}OXY)ACETATE'>O2W</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o2v|3o2v]], [[1c1e|1c1e]], [[1a4k|1a4k]], [[2o5x|2o5x]], [[2o5y|2o5y]], [[2o5z|2o5z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o2v|3o2v]], [[1c1e|1c1e]], [[1a4k|1a4k]], [[2o5x|2o5x]], [[2o5y|2o5y]], [[2o5z|2o5z]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o2w RCSB], [http://www.ebi.ac.uk/pdbsum/3o2w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o2w OCA], [http://pdbe.org/3o2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o2w RCSB], [http://www.ebi.ac.uk/pdbsum/3o2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o2w ProSAT]</span></td></tr>
</table>
</table>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[3D structures of antibody|3D structures of antibody]]
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Verdino, P]]
[[Category: Verdino, P]]
[[Category: Wilson, I A]]
[[Category: Wilson, I A]]
[[Category: Igg antibody fab]]
[[Category: Igg antibody fab]]
[[Category: Immune system]]
[[Category: Immune system]]

Revision as of 04:03, 10 December 2016

Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog

3o2w, resolution 2.55Å

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