5gnr
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==the structure of mini-MFN1 K88A in complex with GDP== | |
| - | + | <StructureSection load='5gnr' size='340' side='right' caption='[[5gnr]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5gnr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GNR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5znt|5znt]], [[5zns|5zns]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gnr OCA], [http://pdbe.org/5gnr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gnr RCSB], [http://www.ebi.ac.uk/pdbsum/5gnr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gnr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN]] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hu, J]] | ||
| + | [[Category: Lou, Z]] | ||
| + | [[Category: Ming, Z]] | ||
[[Category: Rao, Z]] | [[Category: Rao, Z]] | ||
| - | [[Category: | + | [[Category: Yan, L]] |
[[Category: Yu, C]] | [[Category: Yu, C]] | ||
| - | [[Category: | + | [[Category: Bdlp-like fold]] |
| - | [[Category: | + | [[Category: Fusion]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Mitofusin 1]] | ||
Revision as of 10:52, 10 December 2016
the structure of mini-MFN1 K88A in complex with GDP
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Categories: Hu, J | Lou, Z | Ming, Z | Rao, Z | Yan, L | Yu, C | Bdlp-like fold | Fusion | Hydrolase | Mitofusin 1
