3r4b

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==Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911==
==Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911==
<StructureSection load='3r4b' size='340' side='right' caption='[[3r4b]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3r4b' size='340' side='right' caption='[[3r4b]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3r4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R4B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3r4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R4B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=74T:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL+{(2S,3R)-4-[({2-[(1-CYCLOPENTYLPIPERIDIN-4-YL)AMINO]-1,3-BENZOTHIAZOL-6-YL}SULFONYL)(2-METHYLPROPYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}CARBAMATE'>74T</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=74T:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL+{(2S,3R)-4-[({2-[(1-CYCLOPENTYLPIPERIDIN-4-YL)AMINO]-1,3-BENZOTHIAZOL-6-YL}SULFONYL)(2-METHYLPROPYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}CARBAMATE'>74T</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r4b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r4b RCSB], [http://www.ebi.ac.uk/pdbsum/3r4b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r4b OCA], [http://pdbe.org/3r4b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3r4b RCSB], [http://www.ebi.ac.uk/pdbsum/3r4b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3r4b ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3r4b" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
 
[[Category: Nalam, M N.L]]
[[Category: Nalam, M N.L]]
[[Category: Schiffer, C A]]
[[Category: Schiffer, C A]]

Revision as of 11:18, 10 December 2016

Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911

3r4b, resolution 1.90Å

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