3s6b
From Proteopedia
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==Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150== | ==Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150== | ||
<StructureSection load='3s6b' size='340' side='right' caption='[[3s6b]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='3s6b' size='340' side='right' caption='[[3s6b]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3s6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3s6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S6B FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF10_0150 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF10_0150 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s6b RCSB], [http://www.ebi.ac.uk/pdbsum/3s6b PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s6b OCA], [http://pdbe.org/3s6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s6b RCSB], [http://www.ebi.ac.uk/pdbsum/3s6b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s6b ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q8IJP2_PLAF7 Q8IJP2_PLAF7]] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_03174] Removes the N-terminal methionine from nascent proteins.[RuleBase:RU003653] | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Methionyl aminopeptidase]] | [[Category: Methionyl aminopeptidase]] | ||
| - | [[Category: | + | [[Category: Plaf7]] |
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Artz, J D]] | [[Category: Artz, J D]] | ||
Revision as of 11:29, 10 December 2016
Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
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Categories: Methionyl aminopeptidase | Plaf7 | Arrowsmith, C H | Artz, J D | Bountra, C | Crombet, L | Edwards, A M | Hills, T | Hui, R | Lew, J | Structural genomic | Tempel, W | Weadge, J | Weigelt, J | Wernimont, A K | Pita bread fold | Hydrolase | Malaria | Peptidase | Proteolysis | Sgc
