4a4k
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
+ | |||
==Crystal structure of the S. cerevisiae Ski2 insertion domain== | ==Crystal structure of the S. cerevisiae Ski2 insertion domain== | ||
<StructureSection load='4a4k' size='340' side='right' caption='[[4a4k]], [[Resolution|resolution]] 3.25Å' scene=''> | <StructureSection load='4a4k' size='340' side='right' caption='[[4a4k]], [[Resolution|resolution]] 3.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4a4k]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4a4k]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A4K FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a4k RCSB], [http://www.ebi.ac.uk/pdbsum/4a4k PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4k OCA], [http://pdbe.org/4a4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a4k RCSB], [http://www.ebi.ac.uk/pdbsum/4a4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4k ProSAT]</span></td></tr> |
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/SKI2_YEAST SKI2_YEAST]] RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon.<ref>PMID:8321235</ref> <ref>PMID:363683</ref> <ref>PMID:6371496</ref> <ref>PMID:7739552</ref> <ref>PMID:7739557</ref> <ref>PMID:9482746</ref> <ref>PMID:10611222</ref> <ref>PMID:10744028</ref> <ref>PMID:10922069</ref> <ref>PMID:11532933</ref> <ref>PMID:11720286</ref> <ref>PMID:12769863</ref> <ref>PMID:14671320</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Line 15: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 4a4k" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
Line 22: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Atcc 18824]] | ||
[[Category: RNA helicase]] | [[Category: RNA helicase]] | ||
- | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Conti, E]] | [[Category: Conti, E]] | ||
[[Category: Halbach, F]] | [[Category: Halbach, F]] |
Revision as of 18:57, 10 December 2016
Crystal structure of the S. cerevisiae Ski2 insertion domain
|
Categories: Atcc 18824 | RNA helicase | Conti, E | Halbach, F | Rode, M | Dexh helicase | Exosome | Hydrolase | Rna degradation