5lwe

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'''Unreleased structure'''
 
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The entry 5lwe is ON HOLD until Paper Publication
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==Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon==
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<StructureSection load='5lwe' size='340' side='right' caption='[[5lwe]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5lwe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LWE FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79K:VERCIRNON'>79K</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lwe OCA], [http://pdbe.org/5lwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lwe RCSB], [http://www.ebi.ac.uk/pdbsum/5lwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lwe ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CCR9_HUMAN CCR9_HUMAN]] Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
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__TOC__
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</StructureSection>
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[[Category: Bennett, K]]
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[[Category: Christopher, J A]]
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[[Category: Congreve, M]]
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[[Category: Cooke, R M]]
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[[Category: Deflorian, F]]
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[[Category: Dore, A S]]
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[[Category: Errey, J C]]
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[[Category: Jazayeri, A]]
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[[Category: Kean, J]]
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[[Category: Marshall, F H]]
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[[Category: Mason, J S]]
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[[Category: Oswald, C]]
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[[Category: Rappas, M]]
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[[Category: Membrane protein]]

Revision as of 02:17, 11 December 2016

Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon

5lwe, resolution 2.80Å

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