4equ

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==Human STK-10 (LOK) kinase domain in DFG-out conformation with inhibitor DSA-7==
==Human STK-10 (LOK) kinase domain in DFG-out conformation with inhibitor DSA-7==
<StructureSection load='4equ' size='340' side='right' caption='[[4equ]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4equ' size='340' side='right' caption='[[4equ]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4equ]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4equ]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G6I:N-{3-[(3-{4-[(4-METHOXYPHENYL)AMINO]-1,3,5-TRIAZIN-2-YL}PYRIDIN-2-YL)AMINO]-4-METHYLPHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE'>G6I</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G6I:N-{3-[(3-{4-[(4-METHOXYPHENYL)AMINO]-1,3,5-TRIAZIN-2-YL}PYRIDIN-2-YL)AMINO]-4-METHYLPHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE'>G6I</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK10, LOK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK10, LOK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4equ FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4equ OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4equ RCSB], [http://www.ebi.ac.uk/pdbsum/4equ PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4equ FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4equ OCA], [http://pdbe.org/4equ PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4equ RCSB], [http://www.ebi.ac.uk/pdbsum/4equ PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4equ ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4equ" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Larson, E T]]
[[Category: Larson, E T]]

Revision as of 02:44, 11 December 2016

Human STK-10 (LOK) kinase domain in DFG-out conformation with inhibitor DSA-7

4equ, resolution 2.00Å

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