5mdm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural intermediates in the fusion associated transition of vesiculovirus glycoprotein== | |
| - | + | <StructureSection load='5mdm' size='340' side='right' caption='[[5mdm]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mdm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chandipura_virus Chandipura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MDM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mdm OCA], [http://pdbe.org/5mdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mdm RCSB], [http://www.ebi.ac.uk/pdbsum/5mdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mdm ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLYCO_CHAV GLYCO_CHAV]] Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chandipura virus]] | ||
| + | [[Category: Albertini, A A]] | ||
| + | [[Category: Baquero, E]] | ||
[[Category: Bressanelli, S]] | [[Category: Bressanelli, S]] | ||
[[Category: Gaudin, Y]] | [[Category: Gaudin, Y]] | ||
| - | [[Category: | + | [[Category: Class iii viral fusion glycoprotein]] |
| - | [[Category: | + | [[Category: Viral protein]] |
Revision as of 19:20, 15 December 2016
Structural intermediates in the fusion associated transition of vesiculovirus glycoprotein
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