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2k05
From Proteopedia
(Difference between revisions)
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==Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21== | ==Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21== | ||
<StructureSection load='2k05' size='340' side='right' caption='[[2k05]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2k05' size='340' side='right' caption='[[2k05]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k05]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2k05]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K05 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k01|2k01]], [[2k03|2k03]], [[2k04|2k04]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k01|2k01]], [[2k03|2k03]], [[2k04|2k04]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXCL12, SDF1, SDF1A, SDF1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXCL12, SDF1, SDF1A, SDF1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), CXCR4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k05 RCSB], [http://www.ebi.ac.uk/pdbsum/2k05 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k05 OCA], [http://pdbe.org/2k05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k05 RCSB], [http://www.ebi.ac.uk/pdbsum/2k05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k05 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k05 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2k05" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[C-X-C motif chemokine|C-X-C motif chemokine]] | *[[C-X-C motif chemokine|C-X-C motif chemokine]] | ||
| - | *[[CXC chemokine receptor | + | *[[CXC chemokine receptor|CXC chemokine receptor]] |
*[[Stromal Derived Factor 1|Stromal Derived Factor 1]] | *[[Stromal Derived Factor 1|Stromal Derived Factor 1]] | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Peterson, F C]] | [[Category: Peterson, F C]] | ||
[[Category: Veldkamp, C T]] | [[Category: Veldkamp, C T]] | ||
Revision as of 07:24, 23 December 2016
Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21
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Categories: Human | Peterson, F C | Veldkamp, C T | Volkman, B F | Chemokine | Chemotaxis | Cxcl12 | Cxcr4 | Cytokine | G-protein coupled receptor | Glycoprotein | Growth factor | Host-virus interaction | Locked dimer | Membrane | Receptor | Sdf1-alpha | Secreted | Stromal cell derived factor-1 | Sulfation | Sulfotyrosine | Transducer | Transmembrane

