5gmd

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'''Unreleased structure'''
 
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The entry 5gmd is ON HOLD until Paper Publication
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==Crystal structure of Sulfolobus solfataricus diphosphomevalonate decarboxylase in complex with ATP-gamma-S==
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<StructureSection load='5gmd' size='340' side='right' caption='[[5gmd]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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Authors: Unno, H., Hemmi, H., Hattori, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5gmd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GMD FirstGlance]. <br>
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Description: Crystal structure of Sulfolobus solfataricus diphosphomevalonate decarboxylase in complex with ATP-gamma-S
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=DP6:(3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC+ACID'>DP6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gme|5gme]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diphosphomevalonate_decarboxylase Diphosphomevalonate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.33 4.1.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmd OCA], [http://pdbe.org/5gmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gmd RCSB], [http://www.ebi.ac.uk/pdbsum/5gmd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DMD_SULSO DMD_SULSO]] Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.<ref>PMID:23378249</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Diphosphomevalonate decarboxylase]]
[[Category: Hattori, A]]
[[Category: Hattori, A]]
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[[Category: Hemmi, H]]
[[Category: Unno, H]]
[[Category: Unno, H]]
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[[Category: Hemmi, H]]
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[[Category: Atpr]]
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[[Category: Lyase]]
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[[Category: Sulfolobus solfataricus]]

Revision as of 16:22, 2 January 2017

Crystal structure of Sulfolobus solfataricus diphosphomevalonate decarboxylase in complex with ATP-gamma-S

5gmd, resolution 1.50Å

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