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1rbj

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|PDB= 1rbj |SIZE=350|CAPTION= <scene name='initialview01'>1rbj</scene>, resolution 2.700&Aring;
|PDB= 1rbj |SIZE=350|CAPTION= <scene name='initialview01'>1rbj</scene>, resolution 2.700&Aring;
|SITE=
|SITE=
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|LIGAND=
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rbj OCA], [http://www.ebi.ac.uk/pdbsum/1rbj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rbj RCSB]</span>
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[[Category: protein-dna complex]]
[[Category: protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:49:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:25:58 2008''

Revision as of 20:26, 30 March 2008


PDB ID 1rbj

Drag the structure with the mouse to rotate
, resolution 2.700Å
Ligands:
Activity: Pancreatic ribonuclease, with EC number 3.1.27.5
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



RIBONUCLEASE B COMPLEX WITH D(TETRA-(DEOXY-ADENYLATE))


Overview

The structure of a tetragonal crystal of bovine pancreatic RNase B complexed with d(pA)(4) was determined by molecular replacement and difference Fourier methods. This crystal belongs to space group P4(1)2(1)2 and has unit-cell dimensions a = b = 44.5, c = 156.5 A. The model consists of the enzyme and a tetranucleotide with fractional occupancies, suggesting multiple modes of oligonucleotide binding. It does not include any polysaccharide residues or solvent molecules. After refinement at 2.7 A, the R value was 0.163 with acceptable stereochemistry. The model illustrates a set of well defined interactions for substrate binding, particularly between the central dinucleotide and the enzyme.

About this Structure

1RBJ is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structure of a ribonuclease B+d(pA)4 complex., Ko TP, Williams R, McPherson A, Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):160-4. PMID:15299737

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