4qh5
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer== | ==The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer== | ||
<StructureSection load='4qh5' size='340' side='right' caption='[[4qh5]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='4qh5' size='340' side='right' caption='[[4qh5]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qh1|4qh1]], [[4qh4|4qh4]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qh1|4qh1]], [[4qh4|4qh4]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh5 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh5 OCA], [http://pdbe.org/4qh5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qh5 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qh5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ion channels|Ion channels]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 16:57, 4 January 2017
The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer
| |||||||||||
