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4qh1

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==The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate==
==The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate==
<StructureSection load='4qh1' size='340' side='right' caption='[[4qh1]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='4qh1' size='340' side='right' caption='[[4qh1]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=BXA:BROMOACETIC+ACID'>BXA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=BXA:BROMOACETIC+ACID'>BXA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qh5|4qh5]], [[4qh4|4qh4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qh5|4qh5]], [[4qh4|4qh4]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh1 OCA], [http://pdbe.org/4qh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qh1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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==See Also==
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*[[Ion channels|Ion channels]]
== References ==
== References ==
<references/>
<references/>

Revision as of 17:03, 4 January 2017

The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate

4qh1, resolution 3.40Å

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