Fibroins
From Proteopedia
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'''Fibroins''' are proteins that constitute silk fibers<ref>PMID:15132657</ref>. Fibroins are large complex proteins and the specific structural details of those making up different types of silk are different, but all fibroins have some common characteristics. Interesting general information on spider silk and a model of one type of a spider silk molecule is at<ref>[http://en.wikipedia.org/wiki/Spider_silk Wikipedia]</ref>. This model of spider silk shows two repeating domains that all fibroins contain. One domain is characterized as being amorphous, also called flexible, disordered segments, and the other one, symbolized by the boxes, has a highly ordered, repetitive, crystal-like structure. The objective of this exercise is to explicate this <b>ordered</b> domain of fibroins. | '''Fibroins''' are proteins that constitute silk fibers<ref>PMID:15132657</ref>. Fibroins are large complex proteins and the specific structural details of those making up different types of silk are different, but all fibroins have some common characteristics. Interesting general information on spider silk and a model of one type of a spider silk molecule is at<ref>[http://en.wikipedia.org/wiki/Spider_silk Wikipedia]</ref>. This model of spider silk shows two repeating domains that all fibroins contain. One domain is characterized as being amorphous, also called flexible, disordered segments, and the other one, symbolized by the boxes, has a highly ordered, repetitive, crystal-like structure. The objective of this exercise is to explicate this <b>ordered</b> domain of fibroins. | ||
| - | < | + | <load='fibroin.pdb' size='350' side='right' caption='Structure of a model fibroin' scene='Fibroins/Chain_a/1'> |
===Repetitive peptide segment & β-sheet=== | ===Repetitive peptide segment & β-sheet=== | ||
Displayed here is a peptide segment that is present in many fibroin proteins that are found in silk fibers. (<scene name='Fibroins/Chain_a/1'>Initial scene</scene>) It is repeated many times to make up the ordered, repetitive structure of the crystalline domain of the fibroin. | Displayed here is a peptide segment that is present in many fibroin proteins that are found in silk fibers. (<scene name='Fibroins/Chain_a/1'>Initial scene</scene>) It is repeated many times to make up the ordered, repetitive structure of the crystalline domain of the fibroin. | ||
Revision as of 07:56, 8 January 2017
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3D Structures of fibroin
Updated on 08-January-2017
3ua0 – Fib heavy chain – silkworm
2khm – Fib-3 C-terminal – spider NMR
References
- ↑ Sohn S, Strey HH, Gido SP. Phase behavior and hydration of silk fibroin. Biomacromolecules. 2004 May-Jun;5(3):751-7. PMID:15132657 doi:http://dx.doi.org/10.1021/bm0343693
- ↑ Wikipedia
