Protein Rev

From Proteopedia

Revision as of 08:31, 9 January 2017

spinqualitylabelsall models HIV-1 protein Rev (olive green) complex with anti-Rev antibody heavy chain (red) and light chain (aqua) (PDB code 5dhz) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Protein Rev (Rev) or regulator of virion is an HIV-1 accessory protein which overcomes the host cellular mechanism which blocks nuclear-cytoplasm export of incompletely processed mRNA[1]. For more details see HIV and accessory proteins.

3D Structures of protein Rev

Updated on 09-January-2017

3lph – Rev oligomerization and RNA-binding domains – HIV-1
1rpv – Rev RNA-binding domain – NMR
5dhz, 5dhv, 5dhx, 5dhy – Rev + anti-Rev antibody
4pmi – Rev + Rev response element RNA

References

1. ↑ Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14. doi: 10.1007/978-1-62703-670-2_9. PMID:24158817 doi:http://dx.doi.org/10.1007/978-1-62703-670-2_9