Polyhydroxybutyrate synthase

From Proteopedia

---

Revision as of 16:15, 11 January 2017

proteopedia linkproteopedia link

spinqualitylabelsall models Polyhydroxybutyrate synthase catalytic domain {PBD code 5hz2) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image describing Jmol [1] to the rescue. Function Polyhydroxybutyrate synthase (PHBS) or PHB synthase catalyze the polymerization of β-hydroxybutyryl coenzyme A to generate polyhydroxybutyrate[2]. For details see PHB synthase in Rhodobacter sphaeroides. Relevance PHB is of interest as bio-derived and biodegradable plastics. Structural highlights

3D structures of PHB synthase

5t6o, 5hz2 - PHBS catalytic domain - Cupriavidus necator

References

1. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
2. ↑ Jia Y, Yuan W, Wodzinska J, Park C, Sinskey AJ, Stubbe J. Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism. Biochemistry. 2001 Jan 30;40(4):1011-9. PMID:11170423