5hdn
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT== | |
- | + | <StructureSection load='5hdn' size='340' side='right' caption='[[5hdn]], [[Resolution|resolution]] 1.68Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5hdn]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HDN FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
- | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hdg|5hdg]], [[5hdk|5hdk]]</td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdn OCA], [http://pdbe.org/5hdn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hdn RCSB], [http://www.ebi.ac.uk/pdbsum/5hdn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdn ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Feng, H]] | ||
[[Category: Liu, W]] | [[Category: Liu, W]] | ||
- | [[Category: | + | [[Category: Wang, D C]] |
+ | [[Category: Hsf1-dbd]] | ||
+ | [[Category: Transcription]] | ||
+ | [[Category: Ttt]] |
Revision as of 16:26, 18 January 2017
Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
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Categories: Feng, H | Liu, W | Wang, D C | Hsf1-dbd | Transcription | Ttt