5hd8
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of disulfide cross-linked D417C ClC-ec1== | |
- | + | <StructureSection load='5hd8' size='340' side='right' caption='[[5hd8]], [[Resolution|resolution]] 3.15Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5hd8]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HD8 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hd8 OCA], [http://pdbe.org/5hd8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/5hd8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hd8 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI]] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Khantwal, C M]] | ||
[[Category: Maduke, M]] | [[Category: Maduke, M]] | ||
- | [[Category: Mathews, I | + | [[Category: Mathews, I I]] |
- | [[Category: | + | [[Category: Antiporter]] |
+ | [[Category: Membrane exchanger]] | ||
+ | [[Category: Transport protein]] |
Revision as of 00:40, 19 January 2017
Crystal structure of disulfide cross-linked D417C ClC-ec1
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