5hkc
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA== | |
- | + | <StructureSection load='5hkc' size='340' side='right' caption='[[5hkc]], [[Resolution|resolution]] 1.68Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5hkc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKC FirstGlance]. <br> | |
- | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DU:2-DEOXYURIDINE-5-MONOPHOSPHATE'>DU</scene></td></tr> | |
- | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hk3|5hk3]], [[5hjz|5hjz]], [[5hk0|5hk0]]</td></tr> |
- | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkc OCA], [http://pdbe.org/5hkc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkc RCSB], [http://www.ebi.ac.uk/pdbsum/5hkc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkc ProSAT]</span></td></tr> |
- | [[Category: Brennan, R | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/MAZF6_MYCTO MAZF6_MYCTO]] Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the second and third bases in the sequences CUCCU and UUCCU. Neutralized by coexpression with cognate antitoxin MazE6.[UniProtKB:P9WII3] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Brennan, R G]] | ||
+ | [[Category: Yen, T J]] | ||
+ | [[Category: Hydrolase-rna complex]] | ||
+ | [[Category: Mazf]] | ||
+ | [[Category: Toxin-antitoxin system]] |
Revision as of 00:41, 19 January 2017
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA
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