5m0i

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'''Unreleased structure'''
 
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The entry 5m0i is ON HOLD until Paper Publication
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==Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element==
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<StructureSection load='5m0i' size='340' side='right' caption='[[5m0i]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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Authors: Edelmann, F.T., Janowski, R., Niessing, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5m0i]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M0I FirstGlance]. <br>
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Description: Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5m0h|5m0h]]</td></tr>
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[[Category: Edelmann, F.T]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0i OCA], [http://pdbe.org/5m0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m0i RCSB], [http://www.ebi.ac.uk/pdbsum/5m0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SHE2_YEAS1 SHE2_YEAS1]] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity). [[http://www.uniprot.org/uniprot/SHE3_YEAST SHE3_YEAST]] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.<ref>PMID:9809065</ref> <ref>PMID:10359695</ref> <ref>PMID:10212145</ref> <ref>PMID:11032818</ref> <ref>PMID:11101531</ref> <ref>PMID:12499354</ref> <ref>PMID:14691136</ref> <ref>PMID:14561888</ref> <ref>PMID:15328357</ref> <ref>PMID:16890529</ref> <ref>PMID:19429778</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Edelmann, F T]]
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[[Category: Janowski, R]]
[[Category: Niessing, D]]
[[Category: Niessing, D]]
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[[Category: Janowski, R]]
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[[Category: Ash1-mrna]]
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[[Category: Mrna transport]]
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[[Category: She2p]]
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[[Category: Transport protein]]

Revision as of 00:46, 19 January 2017

Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element

5m0i, resolution 2.41Å

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