5m0j
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element== | |
| - | + | <StructureSection load='5m0j' size='340' side='right' caption='[[5m0j]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5m0j]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M0J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5m0h|5m0h]], [[5m0i|5m0i]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0j OCA], [http://pdbe.org/5m0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m0j RCSB], [http://www.ebi.ac.uk/pdbsum/5m0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0j ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SHE2_YEAS1 SHE2_YEAS1]] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Edelmann, F T]] | ||
| + | [[Category: Janowski, R]] | ||
[[Category: Niessing, D]] | [[Category: Niessing, D]] | ||
| - | [[Category: | + | [[Category: Ash1-mrna]] |
| + | [[Category: Mrna transport]] | ||
| + | [[Category: Rna binding protein]] | ||
| + | [[Category: She2p]] | ||
| + | [[Category: She3p]] | ||
Revision as of 00:46, 19 January 2017
Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element
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