5tio
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607== | |
| - | + | <StructureSection load='5tio' size='340' side='right' caption='[[5tio]], [[Resolution|resolution]] 3.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5tio]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TIO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7C6:(3S,3AS,9BS)-2-[(2H-1,3-BENZODIOXOL-5-YL)SULFONYL]-3,5-DIMETHYL-1,2,3,3A,5,9B-HEXAHYDRO-4H-PYRROLO[3,4-C][1,6]NAPHTHYRIDIN-4-ONE'>7C6</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tin|5tin]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tio OCA], [http://pdbe.org/5tio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tio RCSB], [http://www.ebi.ac.uk/pdbsum/5tio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tio ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLRA3_HUMAN GLRA3_HUMAN]] The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chen, H]] | ||
[[Category: Huang, X]] | [[Category: Huang, X]] | ||
| - | [[Category: | + | [[Category: Shaffer, P L]] |
| - | [[Category: | + | [[Category: Ligand-gated ion channel neurotransmitter receptor membrane protein cys-loop receptor]] |
| + | [[Category: Transport protein]] | ||
Revision as of 00:48, 19 January 2017
Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607
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